Standards

IEC 62304 Explained: A Practical Guide for Medical Device Startups

The international standard for medical device software — what it actually requires, what it doesn't, and how to achieve compliance efficiently.

⏱ 10 min read· May 2026· Tolga Ciftci, PreQMS
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IEC 62304 is the international standard governing software lifecycle processes for medical devices. If you're building a software-based medical device for the US, EU, or most regulated markets, you'll need to comply with it. Here's what it actually means in practice.

What is IEC 62304?

Published by the International Electrotechnical Commission, IEC 62304:2006 (amended 2015) defines the lifecycle requirements for medical device software — from planning and requirements through architecture, implementation, verification, maintenance, and problem resolution.

The FDA formally recognises IEC 62304 in its 510(k) guidance, and the EU MDR/IVDR regulations reference it under harmonised standards. In practice: if you're submitting a 510(k) or a CE-marked device, IEC 62304 compliance is expected.

One thing to understand upfront

IEC 62304 doesn't tell you how to write software. It tells you what processes, documents, and records must exist. It's a process standard, not a technical standard. Agile, waterfall, or hybrid — all are compatible with 62304 compliance.

The three safety classes

Everything in IEC 62304 depends on the software safety class of your device. The class is determined by what happens if the software fails:

ClassWorst-case failure consequenceTypical devices
Class ANo injury or damage to health possibleFitness trackers, wellness apps, administrative software
Class BNon-serious injury possibleDiagnostic imaging, monitoring software, drug calculators (with override)
Class CDeath or serious injury possibleInfusion pump controllers, radiation therapy software, ventilator software, surgical robotics

Most startup medical devices fall into Class B or C. If your software makes clinical decisions, controls treatment delivery, or interprets safety-critical sensor data — assume Class C until your hazard analysis says otherwise.

Common mistake: Classifying your software as Class A to reduce documentation burden, without actually performing the hazard analysis. Regulators look at this carefully. Classification without a supporting hazard analysis is a red flag.

The lifecycle processes

IEC 62304 defines these mandatory processes:

1. Software development planning

Before you write code, document how you will develop software. This is your Software Development Plan. It doesn't have to be a 50-page document — a clear description of your lifecycle model, tools, team roles, and how you'll handle deviations is enough.

2. Software requirements analysis

Define what the software shall do. Every requirement must be testable. Safety requirements must be marked as such. This produces your Software Requirements Specification (SRS).

For Class C, requirements must also trace to risk controls in your risk management file.

3. Software architectural design

Class B and C require a documented software architecture — how the system is decomposed into modules. For Class C, each module must be assigned a safety class individually (a Class C system can contain Class A modules).

4. Software detailed design

Class C only — detailed design for each software unit. Think interface definitions, algorithm descriptions, data structures. Not necessarily a line-by-line spec, but enough that the design is auditable.

5. Software unit implementation and verification

Writing and testing individual units. For Class C, each unit must be verified (unit testing). Code reviews count — the standard doesn't mandate automated unit tests, though they're strongly advisable.

6. Software integration and integration testing

Integrating units and testing the integrated system. Must be documented. Your SSTC (System/Software Test Cases) document is the evidence.

7. Software system testing

Testing the complete system against all software requirements. Every requirement must be tested. This is your formal V&V (Verification and Validation) evidence.

8. Software release

Formally releasing a version includes: confirming all activities are complete, all anomalies resolved or risk-accepted, all documentation updated, and a version label applied to the exact build being released.

9. Software maintenance

After release, any software changes — bug fixes, feature additions — must go through change control. Each change gets classified, assessed for impact, and re-verified proportionally. A typo fix in error message text isn't the same as changing a dosing algorithm.

10. Software problem and modification analysis

Your anomaly (bug) tracking process. Problems must be reported, evaluated, and resolved (or risk-accepted). This feeds your Anomaly List — a required output of the 62304 process.

What documentation do you actually need?

Mapping the required records to common document types:

DocumentClass AClass BClass C
Software Development Plan
Software Requirements Spec (SRS)
Software Architecture
Detailed Design
Unit Test Records
Integration Test Records (SSTC)
System Test Records (SSTP)
Traceability Matrix
Anomaly List
Version History

IEC 62304 and ISO 14971

IEC 62304 doesn't stand alone — it explicitly references ISO 14971, the risk management standard for medical devices. Software risk controls defined in your ISO 14971 risk management file must trace to specific software requirements in your SRS, which in turn trace to test cases.

This is the full chain regulators look for: Hazard → Risk Control → SRS Requirement → Test Case → Test Evidence. A gap anywhere in this chain is a finding.

Practical tips for startups

  1. Start classification early. Don't wait until you're preparing your submission to classify your software. It drives every documentation decision.
  2. Don't over-engineer the SDP. A lean Software Development Plan that describes how you actually work is better than a 60-page document that doesn't reflect reality. Auditors can tell.
  3. Traceable from day one. Retrofitting traceability is painful. If you write requirements in a tool that supports linking to test cases, you build the matrix naturally as you work.
  4. Formal reviews on paper. IEC 62304 requires design reviews and code reviews. "We discussed it on a call" isn't sufficient. A brief meeting note with attendees, date, items reviewed, and outcome takes five minutes and is the difference between a passing audit and an observation.
  5. Change control from v1.0. Even before you're under FDA scrutiny, maintain a change log. It's much easier to keep it current than to reconstruct it before your submission.

How long does 62304 compliance take?

For a startup with existing software that wasn't developed under IEC 62304: typically 3–6 months to close the gaps, depending on team size and how much documentation already exists. The most common gaps are:

"IEC 62304 compliance is mostly a documentation discipline problem, not an engineering problem. Most medical device startups are already doing the right things technically — they just haven't written it down in the right format." — Regulatory consultant perspective

IEC 62304-structured documentation in PreQMS

SRS, SSTC, and traceability matrix built around the 62304 lifecycle — not adapted from generic project management tools.

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