AI-powered · IEC 62304 · FDA 510(k)

The 510(k) documentation platform for medical device companies.

Generate submission-ready Software Requirement Specifications (SRS), Software System Test Cases (SSTC), Software System Test Procedures (SSTP) and Traceability documentation. Manage requirements, formal reviews, and compliance in one purpose-built platform.

IEC 62304 compliant out of the box FDA audit trail included Import your existing Word docs

Trusted by medical device companies

HYGIEIA
Unlocking the Power of Insulin
TALIS
Biomedical
Menlo Park, CA
Seraph
Biosciences
Detroit, MI
McLaren
Health Care

Logos shown represent organisations whose documentation projects were supported by our consulting team.

510(k) documentation is broken.

Most medical device teams manage their entire software documentation lifecycle in Word, Excel, and shared drives. Here's what that looks like in practice.

📄
SRS in a shared Word doc
300 requirements, tracked changes turned on, 4 people editing. No version control. No audit trail. Reviewer comments in the margin. Sound familiar?
📊
Traceability in a spreadsheet
500-row Excel file with manual VLOOKUP linking requirements to test cases. Every time a requirement changes, you update it in 3 places. Or forget to.
📧
Review via email chains
Send a PDF to the reviewer. They mark it up and email it back. You incorporate comments. Send again. Two weeks later you have a signed document — maybe.

Built around the standards your auditors check.

Every feature maps to a specific IEC 62304 or FDA requirement. Not a generic doc tool — a purpose-built submission platform.

IEC 62304 FDA 510(k) ISO 14971 21 CFR Part 11 ISO 13485

All your 510(k) documents,
in one platform.

From first requirement to final release signature — PreQMS handles the entire software documentation lifecycle.

📋
Requirements Management (SRS)
Structured requirements with SHALL formatting, rich text, version history, and priority levels. Import from existing Word documents in seconds.
🔗
Full Traceability Matrix
Link requirements to test cases to test procedures. Visual linking mode. See coverage gaps instantly. Export submission-ready matrix in one click.
Formal Review Workflow
Assign qualified reviewers with digital sign-off. Full audit trail. Module locked during review — no undocumented edits. 21 CFR Part 11 compliant.
AI-Powered Generation
Generate requirements from manuals or source code. Auto-generate test cases from SRS. AI reviews each requirement against IEC 62304 rules before your auditor does.
🧪
Test Cases & Procedures
Dedicated SSTC and SSTP module types. Import from Word or Excel. Export as formatted DOCX — ready to drop into your 510(k) technical file.
📦
Baselines & Version Control
Snapshot any module at any point. Release baselines auto-created at sign-off. Every change attributed to a named user with timestamp.
🌳
Fault Tree Analysis (FTA)
Visual fault tree with top-down hazard analysis. Link hazards to SRS requirements. Export for your technical file.
🛡️
Risk Management · ISO 14971
FMEA-style risk assessment linked to software requirements for end-to-end risk coverage. Coming soon.
📊
Submission Readiness Dashboard
Your 510(k) submission readiness at a glance. Which modules are drafted, reviewed, approved, released. What's blocking submission.

Not ready to go it alone?
We do it with you — or for you.

PreQMS combines software with expert-led documentation services. Whether you need a guided setup or a fully managed 510(k) documentation package, our team handles it inside the platform.

Tier 1 · Software
Platform
You and your team use PreQMS to create and manage your own documentation. Full access to all modules, AI review, traceability, and formal sign-off workflows.
All document types (SRS, SSTC, SSTP, FTA)
AI requirement generation & review
Formal review & sign-off workflow
Traceability matrix & baselines
Submission readiness dashboard
Starting from
$199 / seat / month
Billed monthly · scales with your team
Get started
Most popular
Tier 2 · Software + Services
Platform + Guided Setup
Everything in Platform, plus our experts configure your workspace, import and structure your existing documents, run the first AI review pass, and hand it over submission-ready.
Everything in Platform
Expert workspace setup & configuration
Import & structure your existing docs
First AI review pass with expert commentary
Gap analysis against IEC 62304 & FDA expectations
30-day post-setup support
One-time setup fee + Platform
From $2,500 + SaaS
Talk to us
Tier 3 · Fully Managed
Managed Documentation
Our team creates your complete 510(k) software documentation package inside PreQMS. You focus on building the device — we handle the entire regulatory documentation lifecycle.
Full SRS, SSTC, SSTP authoring
Risk management (ISO 14971)
Cybersecurity (AAMI TIR 57)
HIPAA & GDPR auditing
Complete traceability & Design History File
Investor due diligence reports
Project-based pricing
From $15,000
Get a quote
Services we provide
📋
SRS & Software Documentation
System & software requirements, architectural design, design specifications — all per IEC 62304.
🧪
Verification & Validation (V&V)
Test protocols, test cases, and test procedures that satisfy FDA's V&V requirements per IEC 62304.
🛡️
Risk Management · ISO 14971
Software hazard analysis, FMEA, risk control measures, and residual risk evaluation.
🔗
Traceability Matrix
End-to-end traceability from requirements through test cases — built and maintained inside PreQMS.
🔒
Cybersecurity · AAMI TIR 57
Medical device cybersecurity risk management documentation aligned with FDA's latest guidance.
📊
Investor Due Diligence
510(k) readiness assessments for investors evaluating medtech startups. Know exactly where the company stands.
20+
Years of regulatory expertise
0
Rejected 510(k) submissions
500K+
Lines of code documented
3/wk
Regulatory surveys completed
Get in touch
Tell us about your project.
We'll follow up within 1 business day with a recommendation and next steps.

We'll review your project and recommend the right service tier. No commitment required.

From kickoff to submission
in one workflow.

PreQMS maps directly to the IEC 62304 software lifecycle. No customisation — the process is built in.

1

Import or create your SRS

Upload your existing Word document and PreQMS extracts requirements automatically. Or start from IEC 62304 templates.

2

AI reviews every requirement

Catch vague, non-testable, or non-conforming requirements before your submission. Each flagged against specific IEC 62304 rules.

3

Generate test cases automatically

PreQMS reads your SRS and generates a draft SSTC test case document. Build your traceability matrix as you go.

4

Formal review and digital sign-off

Assign qualified reviewers. They approve or comment. Module locked during review. Release creates a baseline automatically.

5

Export submission-ready documents

SRS, SSTC, SSTP, traceability matrix — all formatted for your 510(k) technical file. One click.

Submission readiness — NPS Controller GUI
SRS · System Requirements
Released · Baseline v3 · 47 requirements
SSTC · System Test Cases (v1)
Released · 23 test cases
SSTC · System Test Cases
Released · 884 test cases · Full traceability
SSTP · Test Procedures
In review · Awaiting 1 sign-off
FTA · Fault Tree Analysis
Draft · 12 hazards identified
Risk Analysis · ISO 14971
Not started
Submission readiness
4 of 6 required documents released
67%

Enterprise-grade security.
Transparent AI data handling.

Your requirements and documentation are sensitive. Here's exactly how we protect them.

🔐
Data encryption
Your data is protected in transit and at rest. Railway infrastructure handles encryption at the platform level.
🏢
Tenant isolation
Complete data isolation between organisations. Your data is never shared with or visible to other tenants. Full row-level security.
📋
Full audit trail
Every action logged — who changed what, when, and from where. Built with 21 CFR Part 11 in mind — every action logged with user, timestamp, and full change detail.
🔑
Your own AI key (optional)
Enterprise customers can connect their own Anthropic API key. Your documents are processed under your own API agreement, not ours.
⚡ How AI handles your data
Anthropic does not use API data to train models. Your requirements are never used to improve AI systems.
AI features are opt-in per workspace. You can disable them entirely in your admin settings.
Enterprise customers can use Azure OpenAI or AWS Bedrock — your data never leaves your cloud tenancy.
All AI calls are logged in the audit trail with timestamps and user attribution.

Built for the realities of medical device development.

10×
Faster to create a submission-ready SRS vs. Word
100%
Audit trail on every change, every user, every version
0
Spreadsheets needed for traceability
5 min
To import an existing 500-row SRS from Word

See PreQMS with your own documentation.

Book a 30-minute demo. We'll walk through the platform and import one of your existing documents together.

Book a 30-minute demo

No commitment. We'll reach out within 1 business day if you prefer email — sales@preqms.com

Common questions.

What is a 510(k)?
A 510(k) is an FDA premarket submission that demonstrates your medical device is substantially equivalent to a legally marketed predicate device. For software-based devices, this requires a full software documentation package including SRS, SSTC, SSTP, hazard analysis, and traceability matrix.
What is IEC 62304?
IEC 62304 is the international standard for medical device software lifecycle processes. It defines requirements for software development, maintenance, and documentation — and is the primary technical standard FDA references for software in 510(k) submissions.
Can I import my existing Word documents?
Yes. PreQMS parses your existing SRS, SSTC, SSTP, and test case documents and imports them as structured requirements. Most documents import in under 5 minutes regardless of size.
Does AI training use our data?
No. PreQMS uses Anthropic's API, which does not train models on API data. Your requirements and documents are never used to improve any AI system. Enterprise customers can also use their own API key for full data control.
Does PreQMS replace a full eQMS?
PreQMS is focused on software documentation — SRS, SSTC, SSTP, traceability, and the software-specific parts of your technical file. It is designed to work alongside broader QMS tools (like Greenlight Guru or Qualio), not replace them.
How does the formal review workflow work?
You assign a module to one or more qualified reviewers. The module is locked — no edits allowed during review. Reviewers sign off digitally with Approve, Approve with Notes, or Needs Revision. The full trail is logged and exportable for your submission package.
What document types does PreQMS support?
SRS (Software Requirements Specification), SSTC (System/Software Test Cases), SSTP (System Test Procedures), FTA (Fault Tree Analysis), Use Cases, Risk Analysis, and custom document types.
Is PreQMS HIPAA compliant?
PreQMS handles software documentation — not patient data. HIPAA applies to Protected Health Information (PHI), not technical files or requirements documents. Full encryption, access controls, and audit trails are included for regulatory compliance.

Trusted by medical device software teams.

"
We'd been managing our 510(k) SRS in a shared Word document with tracked changes. The reviewer sign-off process alone took two weeks of emailing PDFs. PreQMS cut that to two days — and our FDA reviewer actually complimented the traceability matrix.

Your next 510(k) starts here.

Join medical device software teams using PreQMS to write better documentation, pass audits faster, and submit with confidence.

Book a demo Explore services →

Need expert help? We offer fully managed documentation services — our team does the work inside the platform.